Ligand design for Rh(iii)-catalyzed C–H activation: an unsymmetrical cyclopentadienyl group enables a regioselective synthesis of dihydroisoquinolones† †Electronic supplementary information (ESI) available: Experimental procedures and compound characterization. CCDC 1021286. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc02590c Click here for additional data file. Click here for additional data file.

Rh(iii)-catalyzed double C–H activation of aldehyde hydrazones: a route for functionalized 1H-indazole synthesis† †Electronic supplementary information (ESI) available. CCDC 1499990. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc03888c Click here for additional data file. Click here for additional data file.

Heptamethylindenyl (Ind*) enables diastereoselective benzamidation of cyclopropenes via Rh(iii)-catalyzed C–H activation† †Electronic supplementary information (ESI) available: Experimental procedures and compound characterization. CCDC 1472771. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc02587k Click here for additional data file. Click here for additional data file. Click here for additional data file.

The diastereoselective coupling of O-substituted arylhydroxamates and cyclopropenes mediated by Rh(III) catalysis was successfully developed. Through ligand development, the diastereoselectivity of this reaction was improved using a heptamethylindenyl (Ind*) ligand, which has been rationalized using quantum chemical calculations. In addition, the nature of the O-substituted ester of benzhydroxa...

Enantioselective palladium(0)-catalyzed intramolecular cyclopropane functionalization: access to dihydroquinolones, dihydroisoquinolones and the BMS-791325 ring system† †Electronic supplementary information (ESI) available: Experimental procedures and characterization of all new compounds. CCDC 1401582. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc01909e Click here for additional data file. Click here for additional data file.

Taddol-based phosphoramidite ligands enable enantioselective palladium(0)-catalyzed C–H arylation of cyclopropanes. The cyclized products are obtained in high yields and enantioselectivities. The reported method provides efficient access to a broad range of synthetically attractive cyclopropyl containing dihydroquinolones and dihydroisoquinolones as well as allows for an efficient enantioselect...

Carbene catalyzed umpolung of α,β-enals: a reactivity study of diamino dienols vs. azolium enolates, and the characterization of advanced reaction intermediates† †Electronic supplementary information (ESI) available: Experimental procedures, compound characterization data, and X-ray crystallographic data of compounds 4b-Et and 4b-Me. CCDC 1014843 and 1014844. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc01027f Click here for additional data file. Click here for additional data file.

A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions† †Electronic supplementary information (ESI) available: Detailed experimental procedures and characterization data for all new compounds. CCDC 1512973–1512975. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc05472b Click here for additional data file. Click here for additional data file.